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Risk-Based Extraction and Leaching Studies for Injectable Drug Products: Addressing Process Impurities, Nitrosamine Formation, and Syringe Siliconization Effects: Poster Presented at PDA Week 2026
PUBMED · 8. 8. 2026
1. PDA J Pharm Sci Technol. 2026 Aug 7;80(4):512-513. doi: 10.5731/pdajpst.2026.26431. Risk-Based Extraction and Leaching Studies for Injectable Drug Products: Addressing Process Impurities, Nitrosamine Formation, and Syringe Siliconization Effects: Poster Presented at PDA Week 2026. Ranjan P(1). Author information: (1)Novavax pranjan@novavax.com. The safety and quality of injectable drug products are influenced not only by formulation and manufacturing processes but also by the containe
Amorphous particles enhance oral exposure-a case study of a poorly soluble compound in preclinical, toxicology and early clinical studies
PUBMED · 8. 8. 2026
Odborné shrnutí bude doplněno po AI zpracování.
What Does the Shape Space of T Cell Epitopes Look Like?
PubMed · V4d immunology · 8. 8. 2026
Immunol Rev — Buytenhuijs F, Schröder G, Textor J
Data-intensive immune network modelling for One Health
PUBMED · 7. 8. 2026
1. Brief Bioinform. 2026 Jul 3;27(4):bbag420. doi: 10.1093/bib/bbag420. Data-intensive immune network modelling for One Health. Hillis R(1)(2), Johari NBA(1), Shirali M(2)(3), Overton IM(1). Author information: (1)Johnston Cancer Research Centre, Queen's University Belfast, Belfast, UK. (2)Agri-Food and Biosciences Institute, Hillsborough, UK. (3)School of Biological Sciences, Queen's University Belfast, Belfast, UK. The immune system plays a critical role in morbidity and mortality. For exa
Systematic Review on Artificial Intelligence in Rheumatology Practice: From Implementation Concerns to Imaging and Clinical Application
PMC · 6. 8. 2026
1. Int J Rheum Dis. 2026 Aug;29(8):e70816. doi: 10.1111/1756-185x.70816. Systematic Review on Artificial Intelligence in Rheumatology Practice: From Implementation Concerns to Imaging and Clinical Application. Barile R(1), Rotondo C(1), Giancaspro G(1), Maruotti N(1), Cantatore FP(1), Corrado A(1). Author information: (1)Department of Medical and Surgical Sciences, University of Foggia, Foggia, Apulia, Italy. BACKGROUND: The integration of artificial intelligence (AI) into healthcare has
Interventional Procedures in Rheumatology: A Comprehensive Review of Current Techniques and Future Prospects
PUBMED · 4. 8. 2026
1. Radiol Clin North Am. 2026 Sep;64(5):813-823. doi: 10.1016/j.rcl.2026.05.002. Epub 2026 Jul 1. Interventional Procedures in Rheumatology: A Comprehensive Review of Current Techniques and Future Prospects. Alshalan A(1), Mansour R(2). Author information: (1)Department of Medical Imaging, King Fahad Specialist Hospital, Dammam, Saudi Arabia. (2)Department of Radiology, Radiation Oncology and Medical Physics, University of Ottawa, Canada. Electronic address: Ramymmansour@outlook.com. Int
Precision Immunosuppression in Kidney Transplantation: A Comprehensive Review
PUBMED · 1. 8. 2026
1. Exp Clin Transplant. 2026 Jul;24(Suppl 2):20-25. doi: 10.6002/ect.MESOT2025.L35. Precision Immunosuppression in Kidney Transplantation: A Comprehensive Review. Argani H(1). Author information: (1)From Urology and Nephrology Research Center, Shahidbeheshti University of Medical Sciences, Tehran, Iran. Individualized immunosuppression represents a paradigm shift in kidney transplant from traditional "trial-and-error" dosing strategies toward individualized regimens. Precision immunosuppr
Three-dimensional printing as a transformative platform for patient-centric pediatric drug delivery: technologies, formulation strategies and clinical translation
PUBMED · 31. 7. 2026
1. Daru. 2026 Jul 30;34(2):52. doi: 10.1007/s40199-026-00630-0. Three-dimensional printing as a transformative platform for patient-centric pediatric drug delivery: technologies, formulation strategies and clinical translation. Phadte P(1), Jeedigunta MK(1), Rao G(1), Chellampillai B(2). Author information: (1)Goa College of Pharmacy, Goa University, Panaji, India. (2)Goa College of Pharmacy, Goa University, Panaji, India. pounbothi@yahoo.com. BACKGROUND: Pediatric patients require age-app
IoT-enabled wireless neural implant for chronic, programmable neuropharmacology and optogenetics
PUBMED · 30. 7. 2026
1. Sci Adv. 2026 Jul 31;12(31):eaee8648. doi: 10.1126/sciadv.aee8648. Epub 2026 Jul 29. IoT-enabled wireless neural implant for chronic, programmable neuropharmacology and optogenetics. Jeong EY(1), Park JW(2), Cho S(1), Han D(1), Kim CY(1)(3), Kim SW(1), Lee W(4), Kim WY(5), Kim JH(2)(5), Jeong JW(1)(6)(7). Author information: (1)School of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea. (2)Department of Medical Science
Formulation development of a biphasic release tablet-in-tablet system containing ketorolac tromethamine
PUBMED · 30. 7. 2026
Odborné shrnutí bude doplněno po AI zpracování.
Assessment of Sorbitol as a Pharmaceutical Excipient in Oral Liquid Pediatric Formulations Submitted to the U.S. FDA
PUBMED · 30. 7. 2026
1. AAPS J. 2026 Jul 28;28(5):124. doi: 10.1208/s12248-026-01265-4. Assessment of Sorbitol as a Pharmaceutical Excipient in Oral Liquid Pediatric Formulations Submitted to the U.S. FDA. Abulwerdi GA(#)(1), Cote B(#)(1), Abdel-Rahman S(1), Fletcher EP(1), Burckart GJ(2). Author information: (1)Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, 20993, USA. (2)Office of Clinical
Kontextově závislá imunitní regulace: mechanistický a AI-umožněný integrační rámec
PubMed · V4d immunology · 30. 7. 2026
Navržený rámec využívá AI k integraci komplexních dat pro pochopení kontextově závislé imunitní regulace. Tento přístup může vést k přesnější diagnostice a vývoji cílenějších terapií pro imunitní onemocnění. Další validace je nezbytná pro plné využití jeho klinického potenciálu.
Machine Learning of Personal Repertoires From Public T Cell Receptors
PUBMED · 27. 7. 2026
1. Immunol Rev. 2026 Aug;341(1):e70145. doi: 10.1111/imr.70145. Machine Learning of Personal Repertoires From Public T Cell Receptors. Malca O(1), Zilberberg A(1), Efroni S(1). Author information: (1)Faculty of Life Sciences, Bar-Ilan University, Ramat Gan, Israel. The T-cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably a
Formulation and evaluation of sustained-release pitavastatin-loaded chitosan nanoparticles for enhanced anti-hyperlipidemic activity
PUBMED · 24. 7. 2026
1. Pak J Pharm Sci. 2026 Oct 1;39(10):3186-3196. doi: 10.36721/PJPS.2026.39.10.295.1. Formulation and evaluation of sustained-release pitavastatin-loaded chitosan nanoparticles for enhanced anti-hyperlipidemic activity. Arshad A(1), Zaman M(2), Riaz H(1), Haider MS(3), Ishaq W(4), Adnan S(5), Masood Z(3), Ahmed H(6), Ameer N(3), Rahman HMA(7), Waqas M(8), Farooq M(3). Author information: (1)Rashid Latif College of Pharmacy, Lahore, Pakistan. (2)Faculty of Pharmacy, University of Central Pu
Non-animal models in undergraduate education: opportunities, applications, and future directions
PUBMED · 23. 7. 2026
1. Immunohorizons. 2026 Jul 10;10(7):vlag032. doi: 10.1093/immhor/vlag032. Non-animal models in undergraduate education: opportunities, applications, and future directions. Teakel S(1), Connolly J(1), Vanniasinkam T(2), Costabile M(3)(4). Author information: (1)School of Agricultural, Environmental and Veterinary Sciences, Charles Sturt University, NSW, Australia. (2)School of Dentistry and Medical Sciences, Charles Sturt University, Sydney, NSW, Australia. (3)School of Pharmacy and Biomed
Development and in vivo pharmacokinetic evaluation of a phospholipid complex self-nanoemulsifying drug delivery system (PLC-SNEDDS) for enhanced oral bioavailability of cannabidiol
PUBMED · 23. 7. 2026
1. Drug Deliv. 2026 Dec 31;33(1):2702143. doi: 10.1080/10717544.2026.2702143. Epub 2026 Jul 22. Development and in vivo pharmacokinetic evaluation of a phospholipid complex self-nanoemulsifying drug delivery system (PLC-SNEDDS) for enhanced oral bioavailability of cannabidiol. Muta T(1), Mukhopadhyay S(1), Noll B(1), Song Y(1), Garg S(1). Author information: (1)School of Pharmacy and Biomedical Sciences, Adelaide University, Adelaide, SA, Australia. Cannabidiol (CBD) exhibits poor oral b
The 2026 British Society for Rheumatology guideline for pain management in people with inflammatory arthritis
PubMed · V4d rheumatology · 21. 7. 2026
Rheumatology (Oxford) — Scott IC, Smith TM, Babatunde O
Machine Learning for TCR Repertoire Epitope Annotation and Pattern Discovery
PUBMED · 20. 7. 2026
1. Immunol Rev. 2026 Jul;340(1):e70143. doi: 10.1111/imr.70143. Machine Learning for TCR Repertoire Epitope Annotation and Pattern Discovery. Vandoren R(1)(2)(3), Van Deuren V(1)(2)(3), Affaticati F(1)(2)(3), Gielis S(1)(2), Laukens K(1)(2), Meysman P(1)(2). Author information: (1)Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerp, Belgium. (2)Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, B
The critical role of artificial intelligence and bioinformatics in accelerating peptide-based vaccine discovery for tackling global infectious diseases
PUBMED · 18. 7. 2026
1. Brief Bioinform. 2026 Jul 3;27(4):bbag260. doi: 10.1093/bib/bbag260. The critical role of artificial intelligence and bioinformatics in accelerating peptide-based vaccine discovery for tackling global infectious diseases. Tholo N(1), Markey G(1), Harrigan R(1), Pandey P(2), Prasad B(3), Barai RS(4), Gibson DS(1), Shukla P(1). Author information: (1)Personalised Medicine Centre, School of Medicine, Ulster University, C-TRIC Building, Altnagelvin Area Hospital, Glenshane Road, Londonderry
[The 2025 Nobel Prize: regulatory T lymphocytes, the long-neglected "immunosuppressive cells". A brief history of a scientific renaissance and its emergence in France]
PUBMED · 18. 7. 2026
Odborné shrnutí bude doplněno po AI zpracování.
Phytotherapeutics self-microemulsifying systems in pellet dosage form for enhanced intestinal drug delivery: formulation, stability, and in-vivo performance
PUBMED · 16. 7. 2026
1. Drug Deliv. 2026 Dec 31;33(1):2702133. doi: 10.1080/10717544.2026.2702133. Epub 2026 Jul 15. Phytotherapeutics self-microemulsifying systems in pellet dosage form for enhanced intestinal drug delivery: formulation, stability, and in-vivo performance. Koutná G(1), Kotouček J(2), Macků J(1), Kubová K(1), Urbanová M(3), Janisová L(3), Šeděnková I(3), Muselík J(1), Vysloužil J(1), Mašek J(2), Mašková E(2), Pavelková M(1), Vetchý D(1), Brus J(3). Author information: (1)Department of Pharma
Optimizing Chitosan-based Posaconazole Dry Powder Formulation Using Box-Behnken Design: The Role of Leucine in Enhancing Performance
PUBMED · 16. 7. 2026
Odborné shrnutí bude doplněno po AI zpracování.
Rational design 2.0: transitioning from static structural biology to computational prioritization and iterative vaccine optimization for RSV
PubMed · V4d immunology · 14. 7. 2026
Front Immunol — Wei X, Chen J, Li Z
Early Nephrology Consultation and Acute Kidney Injury in Hospitalized Patients: A Randomized Clinical Trial
PUBMED · 11. 7. 2026
1. JAMA Netw Open. 2026 Jul 1;9(7):e2622554. doi: 10.1001/jamanetworkopen.2026.22554. Early Nephrology Consultation and Acute Kidney Injury in Hospitalized Patients: A Randomized Clinical Trial. Churpek MM(1)(2), Fatima A(3), Anjorin O(3), Saravanan A(3), Ko BS(3), Gunning S(3), Prochaska ML(3), Puri TS(3), Zisman AL(3), Edelson DP(4), Giurcanu MC(5), Koyner JL(3)(6); Electronic Signal to Prevent Acute Kidney Injury (ESTOP-AKI) Investigative Team. Collaborators: Chen K, Dias M, Gonzalez