ViaLongeVita

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When the real world becomes the trialVIP

Nature Medicine, Published online: 09 July 2026; doi:10.1038/s41591-026-04484-6 Once confined to post-market surveillance, real-world evidence is now being used to emulate trials, guide approvals and even run studies in real time, forcing a rethink of what constitutes a clinical trial.]]>

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Illustration for "When the real world becomes the trial" — longevity and healthy aging, diverse group of adults

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Nature Medicine, Published online: 09 July 2026; doi:10.1038/s41591-026-04484-6 Once confined to post-market surveillance, real-world evidence is now being used to emulate trials, guide approvals and even run studies in real time, forcing a rethink of what constitutes a clinical trial.]]>

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